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Index > Protein center > Cxadr(Gene name) > Rat
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  • Cxadr (Gene name),
  • Coxsackievirus and adenovirus receptor homolog (Protein name ),  CXAR_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cxadr(Car);
    Protein name:
    Coxsackievirus and adenovirus receptor homolog(CAR;rCAR);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Monomer. Probably homodimer is formed 2 molecules on adjacent cells. Interacts with LNX, MPDZ, BAIAP1, DLG4, PRKCABP, TJP1 and CTNNB1. Interacts with DNAJC7. Probably part of a complex containing CXADR, HSP90AA1 and DNAJC7.
    Function:
    Component of the epithelial apical junction complex that is essential for the tight junction integrity. Proposed to function as a homophilic cell adhesion molecule. Recruits MPDZ to intercellular contact sites. Probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN) through adhesive interactions with AMICA1/JAML located in the plasma membrane of PMN.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein Cell junction adherens junction Cell junction tight junction Basolateral cell membrane Single-pass type I membrane protein Localized at the intercellular contacts. In epithelial cells localizes to the apical junction complex composed of tight and adherens junctions. In airway epithelial cells localized to basolateral membrane but not to apical surface.
    Protein Attributes:
    Sequence length:
    365
    Sequence:
    50:
    MALLLCFVLL | CGVADFTSSL | SITTPEQRIE | KAKGETAYLP | CKFTLEPEDQ | 
    100:
    GPLDIEWLIS | PSDNQKVDQV | IILYSGDKIY | DNYYPDLKGR | VHFTSNDVKS | 
    150:
    GDASINVTNL | QLSDIGTYQC | KVKKAPGVAN | RKFLLTVLVK | PSGTRCFVDG | 
    200:
    SGEIGNDFKL | KCEPKEGSLP | LQYEWQKLSD | SQKMPTPWLA | EMTSPVISVK | 
    250:
    NASSEYSGTY | SCTVQNRVGS | DQCMLRLDVV | PPSNRAGTIA | GAVIGTLLAL | 
    300:
    VLIGAILFCC | HKKRREEKYE | KEVHHDIRED | VPPPKSRTST | ARSYIGSNHS | 
    350:
    SLGSMSPSNM | EGYSKTQYNQ | VPSEDFERAP | QSPTLAPAKV | AAPNLSRMGA | 
    365:
    VPVMIPAQSK | DGSIV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat CAR
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    E13929r
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    Packing:
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    ELISA Kit for Rat CAR
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    E13929m
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    Packing:
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    ELISA Kit for Rat CAR
    Cat.:
    E13929h
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    ELISA Kit for Rat CAR
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    CLIA Kit for Rat CAR
    MSDS:
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    CLIA Kit for Rat CAR
    Cat.:
    U13929h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat CAR
    Cat.:
    U13929m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat CAR
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Rat CAR
    Polyclonal Antibody for Rat CAR
    Polyclonal Antibody for Rat CAR
    Polyclonal Antibody for Rat CAR
    Monoclonal Antibody for Rat CAR
    Monoclonal Antibody for Rat CAR
    Monoclonal Antibody for Rat CAR
    Monoclonal Antibody for Rat CAR
    Protein for Rat CAR
    Protein for Rat CAR
    Protein for Rat CAR
    Protein for Rat CAR

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    Precision
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    Linearity
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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "Expression of Coxsackie-adenovirus-receptor and alpha v-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers."
      Fechner H. , Haack A. , Wang H. , Wang X. , Eizema K. , Pauschinger M. , Schoemaker R.G. , van Veghel R. , Houtsmuller A.B. , Schultheiss H.-P. , Lamers J.M.J. , Poller W.
      Gene Ther.6:1520-1535(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-358 (ISOFORM 1);PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY
      strain: Wistar.
      tissue: Liver.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Liver.
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